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sigI [2020-04-21 14:55:09]
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sigI [2020-04-21 14:55:09]

Locus
BSU_13450
Isoelectric point
8.31
Molecular weight
29.04 kDa
Protein length
251 aa Sequence Blast
Gene length
756 bp Sequence Blast
Function
control of a class of heat shock genes
Essential
no
Synonyms
ykoZ

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,411,892 1,412,647

Phenotypes of a mutant

  • temperature-sensitive growth on agar plates PubMed
  • The protein

    Protein family

  • Sigma-70 factor family (according to UniProt)
  • Localization

  • information on binding sites can be found in the PRODORIC2 database
  • Additional information

  • overexpression of SigI suppresses mreB mreBH mbl mutants PubMed
  • Expression and Regulation

    Operons

    Genes
    Description

    Sigma factors

  • SigI: sigma factor, PubMed, in SigI regulon
  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulatory mechanism

  • WalR: activation, PubMed, in WalR regulon
  • Regulation

  • induced at high temperature (SigI, WalR) PubMed
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    Biological materials

    Mutant

  • MGNA-A229 (ykoZ::erm), available at the NBRP B. subtilis, Japan
  • BKE13450 (sigI::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACCTCAGTTCCTCCCTATA, downstream forward: _UP4_TATCTTAAAGGGGTGCTGCA
  • BKK13450 (sigI::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACCTCAGTTCCTCCCTATA, downstream forward: _UP4_TATCTTAAAGGGGTGCTGCA
  • References

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